Essential Blood Tests After 35: How Often Should You Get Checked?
- Syed Abbas
- Mar 19
- 3 min read
As we age, maintaining good health requires more than just diet and exercise—it involves proactive monitoring through regular blood tests. After the age of 35, our bodies begin to experience metabolic and hormonal shifts that may not be immediately noticeable but can significantly impact long-term health. Regular blood tests allow for early detection of potential health concerns, providing an opportunity for timely intervention and prevention.
Why Blood Tests Matter After 35
Many health conditions, including diabetes, heart disease, thyroid imbalances, and nutrient deficiencies, develop gradually. Early detection is key to preventing complications and maintaining optimal well-being. Depending on individual risk factors such as family history, lifestyle, and medical conditions, some tests may need to be conducted more frequently than others.
Annual Blood Tests (or Multiple times a year, if you have a diagnosed condition)
These tests should be part of a routine health assessment:
Complete Blood Count (CBC): Assesses overall blood health, detecting conditions such as anemia, infections, and immune system disorders.
Lipid Profile: Measures cholesterol levels (HDL, LDL, and triglycerides) to assess cardiovascular disease risk.
Fasting Blood Glucose & HbA1c: Essential for identifying early signs of insulin resistance, prediabetes, or diabetes.
Liver Function Test (LFT): Evaluates liver enzymes and function, particularly important for those who consume alcohol, take medications, or have a history of liver disease.
Kidney Function Test (KFT): Measures creatinine and blood urea nitrogen (BUN) to monitor kidney health and filtration capacity.
Thyroid Function Test (TSH, T3, T4): Detects hypothyroidism or hyperthyroidism, which can contribute to fatigue, weight fluctuations, and mood disorders.
Vitamin D & B12 Levels: Deficiencies in these essential nutrients can lead to fatigue, weakened immunity, and neurological symptoms.
Every 2–3 Years (Or As Needed)
These tests may not be required annually but should be monitored periodically unless you have a family history than you may need them more frequently:
Cardiac Risk Markers (CRP, Homocysteine, Lipoprotein (a)): Evaluates inflammation and genetic predisposition to heart disease.
Iron Studies (Ferritin, Transferrin, Iron Levels): Determines iron levels, which are crucial for oxygen transport and energy production. Low levels can contribute to fatigue and cognitive decline.
Hormonal Panel (Testosterone/Estrogen, Cortisol, DHEA): Assesses hormonal imbalances that may affect energy levels, metabolism, and reproductive health.
Autoimmune Markers (ANA, RA Factor, etc.): Detects underlying autoimmune disorders, especially if symptoms such as joint pain, fatigue, or unexplained inflammation are present.
Special Considerations: Who Needs More Frequent Testing?
Certain individuals should undergo more frequent blood tests based on specific risk factors:
Family History of Chronic Diseases: If there is a history of heart disease, diabetes, or cancer, more frequent screening is recommended.
Unexplained Symptoms: Persistent fatigue, sudden weight changes, digestive issues, or chronic pain warrant additional testing.
Lifestyle Factors: Smoking, high stress, poor sleep, and a sedentary lifestyle increase the risk of metabolic disorders and cardiovascular diseases.
Pre-Pregnancy Planning: Women planning for pregnancy should monitor folic acid, iron, and reproductive hormone levels.
Prioritizing Preventive Health
Routine blood tests are an essential part of preventive healthcare. By identifying potential health risks early, individuals can make informed lifestyle and medical decisions that improve their quality of life. It is always advisable to consult with a healthcare provider to determine the most appropriate testing schedule based on personal health history and risk factors.
Take Control of Your Health
Scheduling routine blood tests is a proactive step toward longevity and well-being. Speak with your healthcare provider about your screening needs and make preventive care a priority.
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Important: Nutrition and lifestyle plays an important role in avoiding or managing many of the chronic diseases. If you need help with nutrition and/or lifestyle modification, you can book a consultation with me.

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